Case-Control Studies: Design, Conduct, Analysis

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Oxford University Press, Jan 21, 1982 - 368 pages
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this book is very informative and have thorough details

Contents

Research Strategies
7
12 Observational Studies
10
13 Choosing Among Research Strategies
17
14 Causation
20
15 History of CaseControl Studies
25
Basic Concepts in the Assessment of Risk
27
22 Relative Measures of Disease Occurrence
32
23 Cohort and CaseControl Sampling Schemes
34
55 Summary
143
Sample Size
144
61 Sample Size and Power for Unmatched Studies
145
62 Sample Size and Power with Multiple Controls per Case
150
63 Smallest Detectable Relative Risk
152
64 Optimal Allocation
154
65 Adjustment for Confounding
159
66 Sample Size and Power for PairMatched Studies
160

24 Risk of Disease Attributable to Exposure
40
25 Exposure
45
26 Interpretation of Relative Risk Data Example
49
27 Cumulative Risk of Disease
52
28 Association and Testing for Significance
53
29 Relative Risk as a Measure of the Strength of Association
56
210 Confounding
58
211 Interaction
63
212 Summary
68
Planning and Conducting a Study
69
32 Definition of Cases
71
33 Defining a Control Group
76
34 Methods of Selecting Cases and Controls
80
35 Developing the Research Instrument
86
36 Informed Consent and Confidentiality
92
37 Pilot Testing
94
38 Preparing and Conducting Field Operations
97
39 Preparation for Data Analysis
99
310 Checklist for Protocol Development
101
Matching
105
41 Criteria for Matching
107
42 Overmatching
109
43 Alternatives to Matching
111
44 Effectiveness Matching and its Alternatives
115
45 Expected Number of Matches
117
46 How Closely Should One Match
118
47 Advantages and Disadvantages of Matching
120
48 Summary
122
Sources of Bias
124
52 Bias in the Estimation of Exposure
135
53 Misclassification
137
54 Other Sources of Error
140
67 Sequential CaseControl Studies
163
68 Further Considerations in Estimating Sample Size
165
69 Summary
170
Basic Methods of Analysis
171
71 Unmatched Analysis of a Single 2 X 2 Table
174
72 Adjustment for Confounding
181
73 Assessment of Individual and Joint Effects of Two or More Variables
196
74 Test for Dose Response
200
75 TestBased Confidence Limits
206
76 Matched Analysis with One Control per Case
207
77 Matched Analysis with Two Controls per Case
213
78 Matched Analysis with Three of More Controls per Case
216
79 Estimation of the Etiologic Fraction
220
Multivariate Analysis
227
81 Interpretation of Logistic Parameters
230
82 Logistic Regression for CaseControl Studies
235
83 Indicator Variables
241
84 Estimation of Logistic Parameters
244
85 Discussion of Logistic Models
250
86 Application of Logistic Regression
254
87 Further Topics in Logistic Regression
263
88 Matched Analysis
269
89 Confounder Score
275
810 Loglinear Models
280
Epilogue
291
Appendices
293
Cumulative Normal Frequency Distribution
315
Largest and Smallest Detectable Relative Risks
319
Sample Size for Group Sequential CaseControl Studies
324
References
325
Index
344
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