Fish Physiology: ZebrafishAcademic Press, 2010 M06 23 - 468 páginas This cutting-edge resource includes up-to-date information on zebrafish physiology and the tools used to study it, not only as a model species for studies of other vertebrates but with application for studies of human disease and aquatic toxicology. The utility of zebrafish for physiological research is based on several key features including i) a "fully" sequenced genome, ii) rapid (~3 month) generation times), iii) their capacity to produce large numbers of externally fertilized eggs, iv) optical transparency of embryos and larvae, and v) the applicability of reverse and forward genetics to assess gene function. Gene knockdown in embryos and the production of transgenic strains are now standard techniques being used to assess physiology. This book will be of keen interest not only to the typical readers of Fish Physiology but also to biomedical researchers, toxicologists and developmental biologists.
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Contenido
1 | |
25 | |
Structure and Function of the Zebrafish Visual System | 81 |
Chapter 4 The Zebrafish Inner Ear | 123 |
A Small Fish with a Large Gene Pool | 173 |
Chapter 6 Developmental Physiology of the Zebrafish Cardiovascular System | 249 |
Chapter 7 Respiration | 289 |
Chapter 8 Ionic and AcidBase Regulation | 311 |
Chapter 9 The Zebrafish as a Model for Human Disease | 345 |
Chapter 10 Perspectives on Zebrafish as a Model in Environmental Toxicology | 367 |
441 | |
OTHER VOLUMES IN THE FISH PHYSIOLOGY SERIES | 453 |
COLOR PLATE SECTION | 456 |
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Términos y frases comunes
activin activity adult zebrafish apical axons behavior Biochem Biol calcium cardiac cardiovascular characterization chemical Chen Comp cone CYP1A Danio rerio defects developmental differentiation dorsal effects embryos Endocrinol endothelial environmental enzymes fish formation function gas exchange gene expression genetic genome ghrelin gill goldfish growth hair cells heart hormone human hypothalamus identified induced inner ear involved ionocytes knockdown larvae lateral line mammalian mammals mechanisms membrane metabolism microRNAs molecular morphants morpholino mRNA mutant Natl Acad neural neurogenesis neurons Neurosci nucleus otic otolith oxygen pathways pattern peptide phenotype photoreceptors Physiol physiology pituitary posterior protein receptor regeneration regulation response retina role Rombough screens semicircular canal sensory signaling specific Stainier studies target TCDD tectum telencephalon teleost tissue toxicity Toxicol toxicology transcription factors transgenic transport uptake vascular ventral vertebrates vesicle visual Wang zebrafish zebrafish brain zebrafish Danio rerio zebrafish embryos zebrafish larvae